Visceral Leishmaniasis (VL) is a debilitating, and if left untreated, fatal neglected tropical disease (NTD) causing an estimated 50,000 to 90,000 infections per year in poverty-stricken populations. There is an urgent need for effective, safe, affordable, and field-adapted treatments for VL. However, current World Health Organization (WHO) treatment guidelines recommend different treatment regimens in the Indian subcontinent and the Eastern part of Africa based on varying regional treatment efficacy results.
Through the VL data sharing platform, IDDO provides an opportunity for VL researchers to pool data from different VL clinical trials in order to enhance the statistical power of the available data. A larger pooled dataset will be more effective in determining optimal dose ranges and will provide a deeper insight into VL characteristics.